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Anti -CD11a (Integrin alpha-L, CD11 Antigen-like Family Member A, Leukocyte Adhesion Glycoprotein LFA-1 alpha Chain, LFA-1A, Leukocyte Function-associated Molecule 1 alpha Chain, ITGAL)
Anti -CD11a (Integrin alpha-L, CD11 Antigen-like Family Member A, Leukocyte Adhesion Glycoprotein LFA-1 alpha Chain, LFA-1A, Leukocyte Function-associated Molecule 1 alpha Chain, ITGAL)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
FC |
|
| CD11a is a 170-180kD type I transmembrane glycoprotein also known as LFA-1a chain and integrin aL subunit. CD11a non-covalently associates with integrin b2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non- hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50). | | | Catalog # | C2262-11B | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 0.5ug/10e6 cells in 100ul volume | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1,k | | Clone No | HI111 | | Host | Mouse | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Specificity | Recognizes human CD11a. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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