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You are here:Home » Antibodies » Abs to Integrin » Anti -CD11b (Mac-1, alphaM integrin, Cr3, MO-1, C3bi Receptor)

Anti -CD11b (Mac-1, alphaM integrin, Cr3, MO-1, C3bi Receptor)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IP IH FC
Catalog #C2262-34E
Fusion Partner NSO myeloma cell line
Source Tissue culture supernatant.
ApplicationsFlow cytometry
Immunohistochemical studies of rat frozen tissue sections and paraffin embedded tissue sections following periodate-lysine paraformaldehyde fixation
Immunoprecipitation
Storage and Stability For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at-20°C
Clone TypeMonoclonal
IsotypeIgG2a
Clone No2Q913
HostMouse
SourceRat
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS containing 10mM sodium azide
PurityProtein G affinity chromatography
ImmunogenRat peritoneal macrophages
SpecificityRecognizes most macrophages (including resident peritoneal and activated macrophages), kupffer cells, but only about 35% of alveolar macrophages. The antibody also labels dendritic cells extensively, granulocytes and cells with the morphology of microglia in brain. The antibody precipitates three polypeptides of 150, 103 and 95kD. The antibody inhibits complement mediated rosettes and is probably the rat equivalent of the human receptor for IC3b called CR3.
Important NoteThis product is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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