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You are here:Home » Antibodies » Abs to Integrin » Anti -CD11b, CD18 (Mac-1, alphaM integrin, Cr3, MO-1, C3bi Receptor)

Anti -CD11b, CD18 (Mac-1, alphaM integrin, Cr3, MO-1, C3bi Receptor)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified IP IH FC
Catalog #C2262-34G
ApplicationsSuitable for use in Flow Cytometry, Immunohistochemistry, Immunoprecipitation and as an inhibitor of C3bi binding to its receptor. Other applications have not been tested.
Recommended DilutionFlow Cytometry: 1:25-1:50
Immunohistochemistry (Frozen and PLP-fixed, paraffin sections, not formalin-fixed): Requires protein digestion pre-treatment e.g. trypsin or pronase.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No2Q919
HostRat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid, before the addition of glycerol to 40%.
PurityPurified by Protein A affinity chromatography.
ImmunogenT cell enriched splenocytes from B10 mice.
SpecificityRecognizes the native mouse and human alphaM integrin chain
(170kD, CD11b), which exists as a heterodimer with the beta 2 integrin (95kD, CD18). Stains polymorphonuclear cells, monocytes and NK cells. Variable activity is reported with tissue macrophages. Blocks C3bi binding to its receptor.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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