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You are here:Home » Antibodies » Abs to Integrin » Anti -CD11b (Mac-1, alphaM integrin, Cr3, MO-1, C3bi Receptor) (FITC)

Anti -CD11b (Mac-1, alphaM integrin, Cr3, MO-1, C3bi Receptor) (FITC)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IP IH FC
Catalog #C2262-34K
ApplicationsSuitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested.
Recommended DilutionFlow Cytometry: 10ul per test in 100ul total
Immunohistochemistry: Frozen tissue sections and paraffin embedded tissue sections following periodate-lysine- paraformaldehyde fixation.
Optimal dilutions to be determined by the researcher.
HybridomaNSO myeloma cell line
SourceTissue culture supernatant.
Storage and StabilityStore at 4°C. Do Not Freeze. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No2Q913
HostMouse
SourceRat
ConcentrationNot Determined
FormSupplied as a liquid in PBS, 10mM sodium azide, 1mg/ml BSA. Labeled with FITC.
PurityPuriified by Protein G affinity chromatography.
ImmunogenRat peritoneal macrophages.
SpecificityRecognizes most macrophages (including resident peritoneal and activated macrophages), kupffer cells, but only about 35% of alveolar macrophages. The antibody also labels dendritic cells extensively, granulocytes and cells with the morphology of microglia in brain. The antibody precipitates three polypeptides of 150, 103 and 95kD. The antibody inhibits complement mediated rosettes and is probably the rat equivalent of the human receptor for IC3b called CR3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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