Anti -CD11b (Mac-1, alphaM integrin) (CT)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
Supernatant |
E B IP IH IC FC |
|
| Integrin alpha-M (ITAM, ITGAM, CD11b, MAC-1 alpha subunit, CR3 alpha chain) is the alpha subunit of ITAM/beta-2 complex (CD11b/CD18, Mac-1), a leukocyte adhesion heterodimeric glycoprotein. ITAM belongs to integrin alpha chain family and it is predominately presented in human myeloid cells, NK1 cells, monocytes, and granulocytes. ITAM/beta-2 complex is a receptor for fibrinogen (binding to P1 and P1 peptides of gamma chain), factor X, and ICAM1. ITAM/beta-2 is implicated in adhesive interactions of monocytes, macrophages, and granulocytes. It is also linked to mediation of complement-coated particle uptake. | | | Catalog # | C2262-36H | | Applications | Suitable for use in Flow Cytometry, ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested. | | Recommended Dilutions | Western Blot: 1:1000-1:10,000 | | Immunohistochemistry (Paraffin): 1:100-1:250 | | Immunocytochemistry: 1:100-1:250 | | Flow Cytometry: 1:20 | | Immunoprecipitation: 1:80 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 9E194 | | Host | Rabbit | | Source | Human | | Concentration | Not Determined | | Form | Supplied as a liquid in PBS, pH 7.2, 0.05% BSA, 0.01% sodium azide, 50% Glycerol. | | Purity | Supernatant | | Immunogen | A synthetic peptide corresponding to the C-terminus of human CD11b/ITAM protein. | | Specificity | Recognizes human CD11b, Integrin alpha-M at ~170kD. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
