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You are here:Home » Antibodies » Abs to Integrin » Anti -CD11b (Mac-1, alphaM integrin, Cr3, MO-1, C3bi Receptor) (Biotin)

Anti -CD11b (Mac-1, alphaM integrin, Cr3, MO-1, C3bi Receptor) (Biotin)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
The CD11b/CD18 antigen belongs to the beta2 intergrin family. Other names include Mac-1, Cr3, MO-1 and C3bi receptor. The CD11b molecule functions as a receptor for C3bi complement, clotting factor X, brinogen and ICAM-1. The CD11b antigen is expressed on approximately 30% of human peripheral blood lymphocytes, most natural killer lymphocytes, circulating monocytes, granulocytes, a subset of T-cells and subsets of macrophages (1,2).
Catalog #C2262-45
ApplicationsSuitable for use in Flow Cytometry and in Cell adhesion research. Other applications not tested.
Recommended DilutionFlow Cytometry: 1ug to stain 1x10e6 cells.
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No1.BB.187
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 1% BSA, 0.1% sodium azide. Labeled with Biotin.
PurityPurified by Protein G chromatography.
ImmunogenSynovial cells and human momocytes.
SpecificityRecognizes the alpha subunit of the CD11b/CD18 complex, an alpha/Beta heterodimeric surface glycoprotein on human leukocytes (Mr 165-170kD).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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