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You are here:Home » Antibodies » Abs to CD Markers » Anti -CD21 (CR2, C3d Receptor, EBV Receptor)

Anti -CD21 (CR2, C3d Receptor, EBV Receptor)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant E B IP IH IC FC
CD21 is a single-pass type 2 transmembrane protein that serves as the complement receptor for C3d and the Epstein-Barr virus. It is a member of a family of C3b/C4b binding proteins that regulate complement activation, comprise tandemly repeated 60-75 amino acid sequences, and whose genes map to band q32 on chromosome 1 (1). CD21 interacts with the p53 anti-oncoprotein, the p68 calcium binding protein and the nuclear p120 ribonucleoprotein to regulate their functions. Phosphorylation of CD21 inhibits its interaction with the nuclear p120 ribonucleoprotein (2).
Catalog #C2272-54E
ApplicationsSuitable for use in Flow Cytometry, ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested.
Recommended DilutionsFlow Cytometry: 1:20
Western Blot: 1:2000-1:5000
Immunoprecipitation: 1:50
Immunohistochemistry: 1:250-1:500
Immunocytochemistry: 1:250-1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG
Clone No9E195
HostRabbit
SourceHuman
ConcentrationNot Determined
FormSupplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05% BSA, 0.01% sodium azide, 40% glycerol.
PuritySupernatant
ImmunogenA synthetic peptide corresponding to residues on the C terminus of human CD21.
SpecificityRecognizes human CD21 at ~155kD. Species Crossreactivity: mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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