| CD22 is a type I integral membrane protein and a member of the sialoadhesin family of cell surface receptors. While it is expressed in the cytoplasm as early as the pro-B cell stage, it appears on the cell surface only upon the expression of membrane-bound IgD. It is found on only the most mature B cells and is rapidly lost with terminal differentiation. CD22 functions in B cell differentiation and homotypic adhesion.1-5 |
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| Catalog # | C2272-94D |
| Applications | • Flow cytometry |
| • Immunohistochemistry (frozen sections) |
| Recommended Dilution | Flow Cytometry: 1ug/10e6 cells |
| Optimal dilutions to be determined by the researcher. |
| Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
| Clone Type | Monoclonal |
| Isotype | IgG1 |
| Clone No | 2Q1324 |
| Host | Mouse |
| Source | Human |
| Concentration | ~0.2mg/ml |
| Form | Supplied as a liquid in PBS, 0.1% sodium azide. |
| Purity | Purified |
| Specificity | Recognizes human CD22. |
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| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
