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Anti -CD26 (Dipeptidyl Peptidase IV, DPPIV, ADABP, ADCP2, TP103, DPP IV) (Biotin)
Anti -CD26 (Dipeptidyl Peptidase IV, DPPIV, ADABP, ADCP2, TP103, DPP IV) (Biotin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Purified |
IP IH FC |
|
| CD26 is also known as dipeptidyl peptidase IV (DPP IV) and adenosine deaminase (ADA)-binding protein. It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells. It is upregulated during T-cell activation. CD26 is also expressed on activated B cells, natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. Antibody does not prevent ADA binding to CD26. | | | Catalog # | C2277-07A1 | | Applications | | | Suitable for use in Flow Cytometry, Immunohistochemistry, | | and Immunoprecipitation. Other applications have not been tested. | | Recommended Dilutions | Immunohistochemistry (frozen sections): use PAP, APAAP or three stage immunoperoxidase tequnique on acetone-fixed cryostat sections. | | Flow Cytometry: 1:20 determined on A704 cells | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 6D23 | | Host | Mouse | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in 50mM Tris, pH 7.2, 100mM sodium chloride, 1% BSA, 0.02% sodium azide. Labeled with Biotin. | | Purity | ~95% Purified (SDS-PAGE) | | Immunogen | Human CD26. | | Specificity | Recognizes human CD26 (DPPIV). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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