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You are here:Home » Antibodies » Abs to CD Markers » Anti -CD26 (Dipeptidyl Peptidase IV, DPPIV, ADABP, ADCP2, TP103, DPP IV) (Biotin)

Anti -CD26 (Dipeptidyl Peptidase IV, DPPIV, ADABP, ADCP2, TP103, DPP IV) (Biotin)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified IP IH FC
CD26 is also known as dipeptidyl peptidase IV (DPP IV) and adenosine deaminase (ADA)-binding protein. It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells. It is upregulated during T-cell activation. CD26 is also expressed on activated B cells, natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. Antibody does not prevent ADA binding to CD26.
Catalog #C2277-07A1
Applications
Suitable for use in Flow Cytometry, Immunohistochemistry,
and Immunoprecipitation. Other applications have not been tested.
Recommended DilutionsImmunohistochemistry (frozen sections): use PAP, APAAP or three stage immunoperoxidase tequnique on acetone-fixed cryostat sections.
Flow Cytometry: 1:20 determined on A704 cells
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No6D23
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 50mM Tris, pH 7.2, 100mM sodium chloride, 1% BSA, 0.02% sodium azide. Labeled with Biotin.
Purity~95% Purified (SDS-PAGE)
ImmunogenHuman CD26.
SpecificityRecognizes human CD26 (DPPIV).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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