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You are here:Home » Antibodies » Abs to CD Markers » Anti -CD31 (PECAM-1, Platelet gpIIa Molecule) (FITC)

Anti -CD31 (PECAM-1, Platelet gpIIa Molecule) (FITC)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified IP IH FC
CD31 (PECAM-1, Platelet gpIIa Molecule) is a 130-140kD type I intergral membrance glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. CD31 is constitutively expressed on the surface of endothelial cells where it is concentrated at cell junctoins. CD31 is also expressed at low levels on all leukocytes and platelets. Homotypic interaction of CD31 is impotant in cell-cell interaction, cell-matrix interaction and signal transduction.
Catalog #C2383-26
ApplicationsSuitable for use in Flow Cytometry, Immunoprecipitation, Immunohistochemistry, Blocking and Inhibition. Other applications not tested.
Recommended DilutionFlow Cytometry: 1ug labels 10e6 cells in 100ul.
Immunohistochemistry: Acetone fixation on frozen tissue.
Inhibition: Inhibits the aggregation of L cells transfected with a variant form of CD31.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No390
HostRat
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.1% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
PurityPurified by affinity chromatography.
ImmunogenMouse leukocyte cell line 32D
SpecificityRecognizes mouse CD31 (PECAM-1), a 130-140kD type 1 integral membrane glycoprotein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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