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You are here:Home » Antibodies » Abs to CD Markers » Anti -CD44 (CD 44, CDw44, ECM III, ECMRIII, Epican, Extracellular Matrix Receptor III, GP90 Lymphocyte Homing Adhesion Receptor, HCAM, HCELL, Heparan Sulfate Proteoglycan, Hermes Antigen, HUTCH1, Hyaluronate Receptor, Indian Blood Group, Inlu Related p80 Glycop

Anti -CD44 (CD 44, CDw44, ECM III, ECMRIII, Epican, Extracellular Matrix Receptor III,
GP90 Lymphocyte Homing Adhesion Receptor, HCAM, HCELL, Heparan Sulfate Proteoglycan,
Hermes Antigen, HUTCH1, Hyaluronate Receptor, Indian Blood Group, Inlu Related p80 Glycop

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP IH FC
CD44 is a 90kD type I transmembrane protein, otherwise known as HCAM or CD44s. Various isoforms of CD44 exist. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.
Catalog #C2398-01K
ApplicationsSuitable for use in Flow Cytometry, Immunohistochemistry, Immunoprecipitation and Western Blot. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:50-1:100; 10ul labels 10e6 cells in 100ul
Immunohistochemistry (Frozen): 1:100
Immunohistochemistry (Paraffin): 1:100; Requires antigen retrieval using heat treatment with sodium citrate buffer, pH 6 prior to staining of paraffin sections.
Western Blot: Detects a band at ~80kD in HeLa cell lysate.
Optimal dilutions to be determined by the researcher.
Recommended Negative ControlI1904-83P1: IgG2a Murine Negative Control
Immunohistochemistry Positive ControlHuman Tonstil
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypeMonoclonal
IsotypeIgG2a
Clone No10B1582
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenStimulated human leukocytes.
SpecificityRecognizes human CD44 at ~90kD expressed on leucocytes, erythrocytes, white matter of the brain and some epithelial cells of the breast and small intestine. Reacts with epitope 3, a protease resistant epitope on CD44. Species Crossreactivity: baboon, African green monkey
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCD44 Isoform RC, CD44 Molecule, Cell Surface Glycoprotein CD44


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