Anti -CD44V6 (HCAM, Homing Cell Adhesion Molecule, Pgp-1, Phagocytic Glycoprotein-1,
Hermes Antigen, Lymphocyte Homing Receptor, ECM-III, HUTCH-1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Purified |
E B IP IH FC IF RIA |
|
| The CD44 molecule belongs to a family of cellular adhesion molecule found on a wide range of normal and malignant cells in epithelial, mesothelial and haematopoietic tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (HCAM) molecule. The additional 10 exons (V1 to V10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been shown to be associated with metastasis and poor prognosis in certain human malignancies, such as breast cancer. | | | Catalog # | C2398-88 | | Applications | Suitable for use in RIA, Immunofluorescence, Flow Cytometry, ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry and Functional Blocking. Other applications not tested. | | Recommended Dilution | RIA: 1:5000 | | Immunofluorescence: 1:100-1:200 | | Flow Cytometry: 1:500-1:1000 | | ELISA: 1:1000-1:2000 | | Western Blot: 1:5000-1:10,000 | | Immunohistochemistry (paraffin embedded tissues): 1:150- 1:250 | | Immunoprecipitation: 1:100-1:200 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.01% sodium azide. | | Purity | Purified | | Immunogen | Synthetic peptide corresponding to human CD44v6. | | Specificity | Recognizes human CD44v6 (~200-250kD). Species Crossreactivity: rabbit, porcine, mouse, canine and bovine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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