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C2400-25A Mouse Anti-CD45 (PTPRC, Protein Tyrosine Phosphatase, Receptor Type, C, B220, CD45, CD45 Antigen, CD45R, GP180, LCA, L-CA, Leukocyte Common Antigen Precursor, LY5, T200)

Specifications
References
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG2a
Clone Number
9F609
Grade
Affinity Purified
Applications
FC
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
-20°C

CD45 is a transmembrane tyrosine phosphatase, expressed on nucleated hematopoitic cells, which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing. CD45 functions as a leukocyte membrane receptor signal transduction. It plays an essential role in the regulation of leukocyte activation, development, and function.

Applications
Suitable for use in Flow Cytometry. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Human lymphocytes
Form
Supplied as a liquid in PBS, pH 7.2.
Purity
Purified by Protein G affinity chromatography.
Specificity
Recognizes all isoforms of human CD45 (LCA).
References
Mustelin, T. et al. (2004) Mol. Immunol. 41,687-700 ; Trowbridge, I.S. et. al. (1994) Annu. Rev. Immunol. 12,85-116 ; Justement, L.B. et. al. (1991) Science 252,1839-1842.
USBio References
No references available
Conjugates
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