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You are here:Home » Antibodies » Abs to CD Markers » Anti -CD47 (CD47 Antigen, Antigenic Surface Determinant Protein OA3, Integrin Associated Protein, IAP, Integrin Associated Signal Transducer, Leukocyte Surface Antigen CD47, MER6, OA3, Protein MER6, Rh-related Antigen)

Anti -CD47 (CD47 Antigen, Antigenic Surface Determinant Protein OA3, Integrin Associated
Protein, IAP, Integrin Associated Signal Transducer, Leukocyte Surface Antigen CD47, MER6,
OA3, Protein MER6, Rh-related Antigen)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IP IH FC
CD47, also known as integrin-associated protein, is a 50kD glycoprotein expressed on all hematopoietic cell lines, epithelial cells, endothelial cells, fibroblasts and many tumor cell lines.
CD47 is involved in several cellular processes including regulation of T cell and dendritic cell activation, regulation of neutrophil (PMN) chemotaxis, caspase-independent apoptosis, and may act as a signal transducer in the regulation of cation fluxes across cell membranes. CD47 has been identified as a ligand for the inhibitory macrophage receptor known as signal regulatory protein alpha (SIRPalpha) and as a receptor for thrombospondin-1.
Catalog #C2402-03G2
ApplicationsSuitable for use in Flow Cytometry, Immunohistochemistry (frozen), and Immunoprecipitation. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:25-1:100; 10ul labels 10e6 cells in 100ul
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No10B1693
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenHuman erythrocytes.
SpecificityRecognizes human CD47.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCD47 Glycoprotein, CD47 Molecule


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