Anti -CD47 (CD47 Antigen, Antigenic Surface Determinant Protein OA3, Integrin Associated
Protein, IAP, Integrin Associated Signal Transducer, Leukocyte Surface Antigen CD47, MER6,
OA3, Protein MER6, Rh-related Antigen)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
IP IH FC |
|
| CD47, also known as integrin-associated protein, is a 50kD glycoprotein expressed on all hematopoietic cell lines, epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. | | | CD47 is involved in several cellular processes including regulation of T cell and dendritic cell activation, regulation of neutrophil (PMN) chemotaxis, caspase-independent apoptosis, and may act as a signal transducer in the regulation of cation fluxes across cell membranes. CD47 has been identified as a ligand for the inhibitory macrophage receptor known as signal regulatory protein alpha (SIRPalpha) and as a receptor for thrombospondin-1. | | | Catalog # | C2402-03G2 | | Applications | Suitable for use in Flow Cytometry, Immunohistochemistry (frozen), and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 1:25-1:100; 10ul labels 10e6 cells in 100ul | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b | | Clone No | 10B1693 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Human erythrocytes. | | Specificity | Recognizes human CD47. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | CD47 Glycoprotein, CD47 Molecule |
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