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You are here:Home » Antibodies » Abs to Integrin » Anti -CD49d (Integrin alpha4, VLA4, LHR, Lymphocyte Homing Receptor)

Anti -CD49d (Integrin alpha4, VLA4, LHR, Lymphocyte Homing Receptor)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Highly Purified
CD49d (VLA-4) inhibits adhesion of rat lymphocytes to cytokine-activated endothelial cells. It blocks binding of rat lymphocytes to purified VCAM-1 and to the CS-1 peptide of fibronectin. VLA-4 is a leukocyte integrin which plays an important role in lymphocyte adhesion and activation.
Catalog #C2404-55
ApplicationsSuitable for use in ELISA. Other applications have not been tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
HybridomaHybridization of P3U1 mouse myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeLgG1
Clone No8.S.168
HostMouse
SourceRat
Concentration1mg/ml
FormSupplied as a liquid in PBS.
Purity>95%. Purified from ascites by column chromatography.
ImmunogenRat peritoneal lymphocytes
SpecificityRecognizes rat VLA4 (very late antigen-4) alpha 4 chain (CD49d: 150kD) which is assoclated with beta 2 (CD29; 130kD).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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