You are here:Home
»
Antibodies
»
Abs to CD Markers
»
Anti -CD54 (Intercellular Adhesion Molecule, ICAM-1) (Biotin)
Anti -CD54 (Intercellular Adhesion Molecule, ICAM-1) (Biotin)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Purified |
B IP IH FC |
|
| CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN-gamma, IL-1, TNF-alpha, lipopolysaccharide and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1. | | | Catalog # | C2409-19J | | Applications | Suitable for use in Western Blot, Immunoprecipitation, Flow Cytometry, Immunohistochemistry, and in vitro blocking studies. Other applications have not been tested. | | Recommended Dilution | Flow Cytometry: 1ug/10e6 cells | | Immunohistochemistry: Frozen sections. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b,k | | Clone No | 5K16 | | Host | Rat | | Source | Mouse | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide. Labeled with Biotin. | | Purity | Purified | | Immunogen | Mouse CD54 | | Specificity | Recognizes mouse CD54/ICAM-1, Mr 95kD. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
