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You are here:Home » Antibodies » Abs to CD Markers » Anti -CD56 (NCAM-1, Neural Cell Adhesion Molecule)

Anti -CD56 (NCAM-1, Neural Cell Adhesion Molecule)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IH IC FC
The neural cell adhesion molecule (NCAM/CD56) has been shown to mediate homophilic cell-cell adhesion in the neuroendocrine system with interactions among immunoglobulin-like domains. It is a multifunction transmembrane protein involved in synaptic plasticity, neurodevelopment and neurogenesis. NCAM appears on early embryonic cells and is important in the formation of cell collectives and their boundaries at sites of morphogenesis (1-3). It is preferentially expressed on human NK cells and a subset of T lymphocytes that mediate MHC-unrestricted cell-mediated cytotoxicity (1). Single nucleotide polymorphisms (SNPs) in the NCAM gene are reported to be significantly associated with bipolar disorder in the Japanese population (3).
Catalog #C2410-56C
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and Immunoprecipitation. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:10,000
Immunohistochemistry: 1:500-1:2000
Immunocytochemistry: 1:100-1:250
Flow Cytometry: 1:150
Immunoprecipitation: 1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No9E206
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 50mM Tris-Glycine, pH 7.4, 0.15M sodium chloride, 0.05% BSA, 0.01% sodium azide, 40% glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to residues near the C-terminus of human NCAM/CD56.
SpecificityRecognizes human CD56/NCAM at ~180kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesNCAM-1, N-CAM-1, CD56 antigen


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