Anti -CD61 (ITGB3, Integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), GP3A,
GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
IP IC FC |
|
| The antibody can be used to immunoprecipate a complex of CD41 and CD61. The apparent molecular weight of the GPIIIa by SDS-PAGE in immunoprecipitaton is 105kD reduced and 90kD unreduced (prelabelled surface proteins). Ligands are fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding. The CD41/CD61 complex is also found on endothelial cells, some B cells, monocytes/macrophages and tumor cells. The monocytoid cell line U937 is highly positive. | | | Catalog # | C2414-17 | | Applications | Immunoprecipitation | | Immunocytochemistry (acetone fixation required) | | Flow cytometry | | Inhibits platelet aggregation, 10ug/ml | | Storage and Handling | Maintain between 2 and 8°C, for 12 months | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgM | | Clone No | 2Q800 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in buffer of 0.02M phosphate, 0.25M sodium chloride, pH 7.6, 0.1% sodium azide | | Purity | Purified from ascites by protein A chromatography | | Immunogen | Normal blood mononuclear cells activated by mixed lymphocyte reaction and cultured for 10 days in medium containing IL-2. | | Specificity | Reacts with human integrin beta 3 (GPIIIa, vitronectin receptor beta chain). | | | Important Note | This product is intended for research use only, not for use in human, therapeutic or diagnostic applications. | | Alternate names | Platelet glycoprotein IIIa, ITGB3, GP3A |
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