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You are here:Home » Antibodies » Abs to CD Markers » Anti -CD63 (CD63 Antigen, Granulophysin, LAMP-3, Lysosome-associated Membrane Glycoprotein 3, ME491, Melanoma-associated Antigen ME491, MLA1, Ocular Melanoma-associated Antigen, OMA81H, Tetraspanin-30, TSPAN30, Tspan-30)

Anti -CD63 (CD63 Antigen, Granulophysin, LAMP-3, Lysosome-associated Membrane Glycoprotein
3, ME491, Melanoma-associated Antigen ME491, MLA1, Ocular Melanoma-associated Antigen,
OMA81H, Tetraspanin-30, TSPAN30, Tspan-30)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified IH
CD63, also known as LAMP-3 or ME491 (melanoma- associated antigen), is a member of the tetraspanin superfamily of protein trafficking proteins. CD63 is ubiquitously expressed and found in late endocytic vesicles, but following cell activation is also present on the plasma membrane. CD63 interacts with other membrane proteins or adaptors to regulate activities such as adhesion, migration and degranulation. The 238aa CD63 migrates at 30-60kD, depending on post-translational modification. Extracellular regions of mouse CD63 share 94% and 67% aa identity with rat and human CD63, respectively.
Catalog #C2418-02K
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry: 8-25ug/ml detects CD63 in perfusion fixed frozen sectoins of mouse kidney
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
Clone TypeMonoclonal
IsotypeIgG1
Clone No9H90
HostRat
SourceMouse
Concentration~0.5mg/ml (after reconstitution)
FormSupplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenMouse CD63-transfected HEK293 human embryonic kidney cells (aa1-238; Accession #P41731).
Species Sequence HomologyRat, 94%; human, 67%.
SpecificityRecognizes mouse CD63.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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