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You are here:Home » Antibodies » Abs to Receptors, Scavenger » Anti -CD68 (DKFZp686M18236, GP110, Macrophage Antigen CD68, Macrosialin, Scavenger Receptor Class D Member 1, SCARD1)

Anti -CD68 (DKFZp686M18236, GP110, Macrophage Antigen CD68, Macrosialin, Scavenger
Receptor Class D Member 1, SCARD1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant IH
CD68 is a 110kD transmembrane glycoprotein of unknown function highly expressed in all cells of the mononuclear phagocyte lineage including monocytes and tissue resident macrophages. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue and organ specific lectins or selectins. CD68 belongs to a growing family of hematopoietic mucin-like molecules, including leukosialin and the lymph node high endothelial ligand for L-selectin GlyCAM- I. The protein is localized to endosome or lysosome-like structure. It is one of 9 genes in a 140kb region of the human chromosome 17p13. Alternative splicing of the gene encoding the protein results in multiple transcripts encoding different isoforms. The protein is highly expressed in bone marrow, colon, small intestine, spleen, testis, trachea and cutaneous T-cell lymphoma.
Catalog #C2423-05S
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 1:10-1:40
Optimal dilutions to be determined by the researcher.
Positive ControlTonsil
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No11E107
HostMouse
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.05% sodium azide.
PuritySupernatant
ImmunogenGaucher cells. Cellular Localization: Cell membrane.
SpecificityRecognizes human CD68.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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