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You are here:Home » Antibodies » Abs to CD Markers » Anti -CD86 (Activation B7-2 Antigen, B70, B7-2, BU63, CD28LG2, CTLA-4 Counter-receptor B7.2, FUN-1, LAB72, MGC34413, T-lymphocyte Activation Antigen CD86 Precursor)

Anti -CD86 (Activation B7-2 Antigen, B70, B7-2, BU63, CD28LG2, CTLA-4 Counter-receptor
B7.2, FUN-1, LAB72, MGC34413, T-lymphocyte Activation Antigen CD86 Precursor)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified B IP IH FC
CD86, also known as B70/B7-2, is a 80kD type I integral membrane protein and a member of the immunoglobulin superfamily. It is expressed at high levels on resting monocytes and dendritic cells and at very low levels on resting B and T lymphocytes. Activation of B cells, T cells and monocytes leads to upregulation of CD86 expression. Like CD80, CD86 is a ligand of CD28 and CD152. The interactions of CD86 (and CD80) with CD28 provides important costimulatory signals to T cells activated via the CD3/TCR complex. CD86 is expressed earlier than CD80 and appears to dominate in the primary immune response.
Catalog #C2438-20A
ApplicationsSuitable for use in Flow Cytometry, Immunoprecipitation, Immunohistochemistry and Western Blot. Other applications have not been tested.
Recommended DilutionsFlow Cytometry: 1ug/10e6 cells
Immunohistochemistry: Frozen sections
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypeMonoclonal
IsotypeIgG1
Clone No5K246
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, sodium azide
PurityPurified
SpecificityRecognizes human CD86.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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