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You are here:Home » Antibodies » Abs to Transport Proteins » Anti -CD92 (CDw92, isoform 3, CTL1) (PE)

Anti -CD92 (CDw92, isoform 3, CTL1) (PE)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
CDw92 (isoform 3), also known as CTL1, a 70kD multi-pass membrane protein, expressed by monocytes, neutrophils, certain myeloid and T cell lines, and weakly by endothelial cells, fibroblasts and epithelial cells. CDw92 is a member of the choline transporter-like protein family, so called due to their involvement in the efficient supply/transport of the natural amine choline, a vital cell nutrient required for the synthesis of cell membrane phospholipid components and the neurotransmitter acetylcholine. Reported to augment the LPS-induced production of IL-10 by monocyte-derived dendritic cells Mo-DCs), and the reduced expression of CDw92 by Mo-DCs treated with ionomycin or calcium ionophore, can be reinduced in the presence of IL-10.
Catalog #C2438-27
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionsFlow Cytometry: Neat-1:10. Use 10ul to label 1x10e6 cells in 100ul.
Optimal dilutions to be determined by the researcher.
HybridomaSpleen cells from immunized Balb/c mice were fused with cells of the X63-Ag8.653 myeloma cell line.
Storage and StabilityLyophilized powder may be stored at 4°C. Stable for 12 months. Reconstitute with sterile ddH2O. Aliquot and store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No10B2144
HostMouse
SourceHuman
ConcentrationNot determined.
FormSupplied as a lyophilized powder from PBS, pH 7.4, 1% BSA, 5% sucrose, 0.09% sodium azide. Labeled with Phycoerythrin (PE). Reconstitute with 1ml sterile ddH2O.
PurityPurified by Protein G affinity chromatography.
ImmunogenMV4-11 acute monocyte leukemia cells
SpecificityRecognizes the C-terminal variant of human CDw92 (isoform 3).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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