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Anti -CD92 (CDw92, isoform 3, CTL1) (PE)
Anti -CD92 (CDw92, isoform 3, CTL1) (PE)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
FC |
|
| CDw92 (isoform 3), also known as CTL1, a 70kD multi-pass membrane protein, expressed by monocytes, neutrophils, certain myeloid and T cell lines, and weakly by endothelial cells, fibroblasts and epithelial cells. CDw92 is a member of the choline transporter-like protein family, so called due to their involvement in the efficient supply/transport of the natural amine choline, a vital cell nutrient required for the synthesis of cell membrane phospholipid components and the neurotransmitter acetylcholine. Reported to augment the LPS-induced production of IL-10 by monocyte-derived dendritic cells Mo-DCs), and the reduced expression of CDw92 by Mo-DCs treated with ionomycin or calcium ionophore, can be reinduced in the presence of IL-10. | | | Catalog # | C2438-27 | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilutions | Flow Cytometry: Neat-1:10. Use 10ul to label 1x10e6 cells in 100ul. | | Optimal dilutions to be determined by the researcher. | | Hybridoma | Spleen cells from immunized Balb/c mice were fused with cells of the X63-Ag8.653 myeloma cell line. | | Storage and Stability | Lyophilized powder may be stored at 4°C. Stable for 12 months. Reconstitute with sterile ddH2O. Aliquot and store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b | | Clone No | 10B2144 | | Host | Mouse | | Source | Human | | Concentration | Not determined. | | Form | Supplied as a lyophilized powder from PBS, pH 7.4, 1% BSA, 5% sucrose, 0.09% sodium azide. Labeled with Phycoerythrin (PE). Reconstitute with 1ml sterile ddH2O. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | MV4-11 acute monocyte leukemia cells | | Specificity | Recognizes the C-terminal variant of human CDw92 (isoform 3). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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