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C2445-44G Mouse Anti-CD102 (Intercellular Adhesion Molecule 2, ICAM-2, ICAM2)

Specifications
References
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG2a,k
Clone Number
CBR-IC2/2
Grade
Affinity Purified
Applications
FC IHC IP
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
-20°C

CD102 is a 55kD type I transmembrane glycoprotein, belongs to immunoglobulin superfamily, also known as Intercellular Adhesion Molecule-2, or ICAM-2. CD102 is constitutively expressed on vascular endothelial cells, some lymphocytes, monocytes, and platelets. CD102 is thought to be involved in lymphocyte recirculation and in costimulation of immune response. CD102 is a counter receptor of LFA-1 (CD11a/CD18), DC-SIGN and MAC-1.

Applications
Suitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation. Other applications not tested.
Recommended Dilution
Flow Cytometry: ≤2ug/10e6 cells in 100ul Immunohistochemistry: Frozen Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ICAM-2 cDNA transfected COS cells
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by affinity chromatography.
Specificity
Recognizes human CD102. Species Crossreactivity: African Green, Baboon, Cynomolgus, Rhesus
References
1.Weber, K.S.C.,et al.2004.Inflammation.28:177. 2.Barclay,A.,et al.1997 The Leukoycte Antigen FactsbookAcademic Press. 3. Casasnovas, J.M.,et al.1999.PNAS96:3017. 4. Diamonds, M.S.set al1990. J. Cell Biol.111:3129. 5. DeFougerolles A.R.,et al.1991.J. Exp.Med.174:253. 6. Van Herpen C.ML.,et al.2005.Clin. Cancer Res.11:1899.
USBio References
No references available
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