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You are here:Home » Antibodies » Abs to CD Markers » Anti -CD104 (CD104 Antigen, Integrin beta-4, Integrin beta4, ITGB4, AA407042, C230078O20)

Anti -CD104 (CD104 Antigen, Integrin beta-4, Integrin beta4, ITGB4, AA407042, C230078O20)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified E IP FC
CD104 is a 205kD type I transmembrane glycoprotein, known as integrin b4 chain or b4 integrin, that associates with integrin a6 (CD49f) forms a6/b4 (CD49f/CD104) heterodimer. CD104 is expressed on epithelial cells (especially on the proliferative basal layer epithelial cells in skin), endothelial cells, Schwann cells, certain tumor cells and a subset of pre-T cells. CD49f/CD104 is an adhesion receptor for laminins (especially laminin 5) and keratin filaments and is involved in the regulation of hemidesmosome formation and of cell proliferation and activation.
Catalog #C2446-01L1
ApplicationsSuitable for use in ELISA, Flow Cytometry and Immunoprecipitation. Other applications not tested.
Recommended DilutionFlow Cytometry: 0.25ug/10e6 cells in 100ul volume
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a,k
HostRat
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenTumor-associated antigen TSP-180 from BALB/c lung carcinoma
SpecificityRecognizes mouse CD104.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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