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Anti -CD104 (CD104 Antigen, Integrin beta-4, Integrin beta4, ITGB4, AA407042, C230078O20) (FITC)
Anti -CD104 (CD104 Antigen, Integrin beta-4, Integrin beta4, ITGB4, AA407042, C230078O20)
(FITC)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Affinity Purified |
FC |
|
| CD104 represents the integrin beta4 subunit that associates non-covalently with integrin alpha6 (CD49f) to form the alpha6beta4 integrin heterodimer.2, 3 The alpha6beta4 complex is expressed on the basal surface of a variety of epithelial cell types, particularly on stratified squamous epithelia. It is also found in peripheral nerves, in certain subsets of endothelial cells, and on immature thymocytes, and has been found to be associated with a number of malignant tissues.3-5, 6 Hemidesmosomal alpha6beta4 plays an important role in the adhesion of epithelial cells to basement membranes via interactions with laminin and/or kalinin anchoring filaments.7 It is not known if the antibody can block this adhesion. | | | Catalog # | C2446-02F | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilution | Flow Cytometry: Neat-1:5; 10ul labels 10e6 cells in 100ul | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 10B527 | | Host | Rat | | Source | Mouse | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC). | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | TSP-180 purified from Balb/c murine carcinoma. | | Specificity | Recognizes mouse CD104. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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