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You are here:Home » Antibodies » Abs to CD Markers » Anti -CD104 (CD104 Antigen, Integrin beta-4, Integrin beta4, ITGB4, AA407042, C230078O20) (PE)

Anti -CD104 (CD104 Antigen, Integrin beta-4, Integrin beta4, ITGB4, AA407042, C230078O20)
(PE)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified FC
Mouse integrin beta 4 (CD104) is a 200kD glycoprotein that can associate with integrin alpha 6 (CD49f) to form a heterodimer on the cell surface. Expression of CD104 is localised to the basal region of a wide variety of epithelial cells. In mice, CD104 is also expressed on peripheral neurones, carcinoma cell lines and a subset of endothelial cells. The alpha 6 beta 4 (CD49f/CD104) integrin has been identified as a component of hemidesmosomes in stratified squamous epithelium where it plays an important role in the adhesion of epithelia to basement membrane. Studies suggest that the CD49f/CD104 integrin is involved in cell matrix adhesion but expression of the CD49f/CD104 integrin in endothelial cells is thought to have a different function.
Catalog #C2446-02H
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: Neat-1:5; 10ul labels 10e6 cells in 100ul
Optimal dilutions to be determined by the researcher.
Recommended Negative ControlI1904-82H1: IgG2a, Rat Negative Control (PE)
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No10B528
HostRat
SourceMouse
ConcentrationNot determined
FormSupplied as a lyophilized powder from PBS, pH 7.4, 1% BSA, 5% sucrose, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE). Reconstitute with 1ml ddH2O.
PurityPurified by Protein G affinity chromatography.
ImmunogenTSP-180 purified from Balb/c murine carcinoma.
SpecificityRecognizes mouse CD104.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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