Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to CD Markers » Anti -CD105 (Endoglin, gp160, TGF beta1,3 Receptor) (Biotin)

Anti -CD105 (Endoglin, gp160, TGF beta1,3 Receptor) (Biotin)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Rat Purified B IC FC
CD105/endoglin is a disulfide-linked type II transmembrane homodimer that is predominantly expressed on vascular endothelial cells. It is also found on pre-erythroblasts, macrophages and lymphoid and myeloid leukemic cells.2 Both mouse and human CD105 exhibit > 70% sequence homology in their cytoplasmic domains with type III transforming growth factor beta (TGFb) receptor.3 CD105 has been shown to be one of several receptors for the various isoforms of TGFb, which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells and control of the immune response.4
Catalog #C2446-50D
ApplicationsSuitable for use in Identification and enumeration of CD105 + cells by Flow Cytometry, Immunocytochemistry and Western Blot. Other applications have not been tested.
Recommended DilutionFlow Cytometry: 1ug/10e6 cells
Immunocytochemistry: frozen sections
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%) aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No5K262
HostRat
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS. Conjugated to Biotin.
PurityPurified
ImmunogenInflamed mouse skin
SpecificityRecognizes mouse endoglin, Mr 90kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links