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Anti -CD105 (Endoglin, gp160, TGF beta1,3 Receptor) (PE)
Anti -CD105 (Endoglin, gp160, TGF beta1,3 Receptor) (PE)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
IH FC |
|
| Human CD105 (endoglin) is a homodimeric membrane glycoprotein virtually restricted to endothelial cells, and present on some leukemia cells and minor subsets of bone marrow cells. CD105 binds to TGF-b1 and b3 with high affinity. | | | Catalog # | C2446-50E3 | | Functional Application | Antibody will augment binding of TGF-b1 to CD105 expressing leukemia cells. | | Applications | Suitable for use in Flow Cytometry, Immunohistochemistry. Other applications not tested. | | Recommended DilutionOptimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only pror to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 7H217 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in 50mM Sodium Phosphate pH 7.5, 500mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Membrane preparation of human B-lineage leukemia cells | | Specificity | Recognizes a CD105 homodimer with a molecular weight of about 160kD. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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