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You are here:Home » Antibodies » Abs to CD Markers » Anti -CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1, INCAM-110)

Anti -CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1, INCAM-110)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified IP IH IF
Human vascular cell adhesion molecule (VCAM-1, 110kD) whose ligand is VLA4 (CD49d/CD29, alpha 4/beta 1 integrin subunits) is distributed across non leukocyte and leukocyte cells e.g. neural crest and broblasts, B cells, T cells, monocytes and large granular lymphocytes.
Catalog #C2446-79
ApplicationsSuitable for use in studies of Cell-cell interaction, Cell adhesion assays, Inhibition of lymphopoiesis in Whitlock-Witte long term marrow cultures, Immunoprecipitation, Immuno uorescence and Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry: Does not work on paraffin sections.
Optimal dilutions to be determined by researcher.
SourceTissue culture supernatant
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No1.BB.619
HostRat
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 10mM sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenStromal cells from mouse bone marrow
SpecificityRecognizes mouse vascular adhesion molecule (VCAM-1), single chain glycoprotein of Mr100-kD (under reducing conditions). VCAM-1 is present on the +/+ 2.4 stromal cell clone, large cells in bone marrow and a subset of thymic macrophages. The stromal cell antigen is also detectable on the EOMA and BMS2 endothelial cell lines. Reacts with all known isoforms of mouse VCAM-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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