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You are here:Home » Antibodies » Abs to Stem Cell Research » Anti -CD133 (Biotin) (AC133, Antigen AC133, CD133, CD133 Antigen, CD133 Retinal Degeneration, CORD12, MCDR2, MSTP061, Prominin 1, Prominin-1, PROM1, PROM, Prominin-like Protein 1, PROML1, RP41, STGD4)

Anti -CD133 (Biotin) (AC133, Antigen AC133, CD133, CD133 Antigen, CD133 Retinal
Degeneration, CORD12, MCDR2, MSTP061, Prominin 1, Prominin-1, PROM1, PROM, Prominin-like
Protein 1, PROML1, RP41, STGD4)

Pricing

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Specifications

Clone Host Grade Applications
Rat Affinity Purified FC
CD133 (also known as Prominin-1 or AC133) is a 120 kD pentaspan glycoprotein with 5 transmembrane domains which localize to cellular protrusions. CD133 was initially described as a surface antigen specific for human hematopoietic stem cells and as a marker for murine neuroepithelial cells and some embryonic epithelia. Later on, CD133 was found on other stem cells including endothelial progenitor cells, glioblastomas, neuronal, and glial stem cells. In addition to hematopoietic stem cells, CD133 was found on cancer cells, such as some leukemia cells and brain tumor cells. It also has been detected at low levels in the kidney, pancreas, placenta, and fetal liver tissue. Although the biological function of CD133 is not conclusive, CD133 has been extensively used as a stem cell marker for normal and cancerous tissues.
Catalog #C2514-90H
ApplicationsSuitable for use in Flow Cytometry. Other applications have not been tested.
Recommended DilutionFlow Cytometry: 1.0ug / 10e6 cells in 100ul volume
Optimal dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone Type
SourceMouse
IsotypeIgG2a, lambda
Clone12J16
Concentration~0.5mg/ml
Immunogen
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Labeled with Biotin.
PurityPurified by affinity chromatography.
SpecificityRecognizes mouse CD133.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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