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CD134 IgG2a Fc, Fusion Protein (OX40) (Preservative Free)
CD134 IgG2a Fc, Fusion Protein (OX40) (Preservative Free)
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| Human CD134 (OX40) (ACT35) is an activation-associated antigen which is predominantly expressed on activated CD4 positive cells. CD134 antigen is a member of the tumor necrosis factor (TNF) receptor family of molecules and may be involved with regulating T cell-dependent B cell proliferation and differentiation (2). | | | Catalog # | C2515-26AX | | Human CD134(OX40)-muIg Fusion Protein* | | Molecular Structure | A soluble molecule consisting of the extracellular (177aa) domain of human CD134 fused to the murine IgG2a Fc (233aa). | | Applications | Suitable for use in ELISA and Flow Cytometry. CD134-muIg fusion protein blocks binding of anti-human CD134 to human tumor cells. Other applications not tested. | | Recommended Dilution ELISA | C2515-26AX was reactive in EIA using a Goat-anti-mouse-Ig antibody capture, folowed by detection using C2515-19A and Streptavidin/HRP. It was also reactive utilizing C2515-40F followed by C2259-11B for detection. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 45.6kD | | Source | CHO cells | | Purity | Purified by size exclusion chromatography. | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in 50mM sodium phosphate, pH 7.5, 100mM potassium chloride, 100mM sodium chloride.. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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