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You are here:Home » Molecular Biology » MB-CD Markers » CD137 IgG1 Fc, Fusion Protein (4-1BB, TNFRSF9, 4-1BB ligand receptor, CD137, CD137 antigen, CDw137, ILA, MGC2172, T-cell antigen 4-1BB homolog, T-cell antigen ILA, Tumor necrosis factor receptor superfamily member 9 precursor) (Biotin)

CD137 IgG1 Fc, Fusion Protein (4-1BB, TNFRSF9, 4-1BB ligand receptor, CD137, CD137
antigen, CDw137, ILA, MGC2172, T-cell antigen 4-1BB homolog, T-cell antigen ILA, Tumor
necrosis factor receptor superfamily member 9 precursor) (Biotin)

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Specifications

Human CD137 (4-1BB) is expressed on activated T cells within 24-48 hours of activation (3). CD137 is a type I membrane protein and a member of the tumor necrosis factor receptor superfamily (1,2). CD137 appears to be important for T cell proliferation and survival (4).
Catalog #C2548-39R
Functional Application CD137 Ig fusion protein blocks binding of anti-human CD137 to activated CEM human tumor cells and also binds to CD137 Ligand on Raji cells. 
Human CD137(4-1BB) huIg/Biotin Fusion Protein*
Molecular Structure A soluble 55 kd fusion protein consisting of the extracellular (186aa) domain of human CD137 (4-1BB) fused to human IgG1 Fc (4).
Transfectant Cell Line CHO
ApplicationsSuitable for use in ELISA, Flow cytometry. Other applications not tested.
Recommended Dilution Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight44.1kD
SourceCHO cells
PurityPurified by Protein A affinity chromatography.
Concentration~0.5mg/ml
FormSupplied as a liquid in FBS, 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.04% NaN3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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