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Specifications

Clone Host Grade Applications Monoclonal Mouse IH

CD163 is a type I membrane protein also known as M130 antigen, Ber-Mac3, Ki-M8 or SM4. CD163 protein is restricted in its expression to the monocytic/macrophage lineage. It is reported to be present on all circulating monocytes and most tissue macrophages except those found in the mantle zone and germinal centers of lymphoid follicles, interdigitating reticulum cells and Langerhans cells. In addition, multinucleated cells within inflammatory lesions are reported not to express CD163 protein. The protein is upregulated by glucocorticoids and downregulated by the immunosuppressant cyclosporin A and phorbol esters.
Catalog #	C2548-89G1
Applications	Suitable for use in Immunohistochemistry. Other applications not tested.
Recommended Dilution	Optimal dilutions to be determined by the researcher.
Positive Control	Tonsil
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	N/A
Clone Type	Monoclonal
Isotype	IgG1
Clone No	8J629
Host	Mouse
Source	Human
Concentration	Not Determined
Form	Supplied as a liquid in PBS.
Purity	Ascites
Immunogen	Human CD163 antigen. Cellular Localization: Membrane
Specificity	Recognizes human CD163 antigen.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.