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You are here:Home » Antibodies » Abs to Cell Division Cycle (CDC) » Anti -CDC23/APC8 (CDC23, CDC-23, Cell division cycle 23, APC8, APC-8, Anaphase-promoting complex subunit 8)

Anti -CDC23/APC8 (CDC23, CDC-23, Cell division cycle 23, APC8, APC-8, Anaphase-promoting
complex subunit 8)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IP
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
Catalog #C2550-11A
ApplicationsSuitable for use in ELISA, Western Blotting, Immunoprecipitation. Other applications not tested.
Recommended DilutionWestern Blot: 1:2000 to 1:10,000
Immunoprecipitation: 2-5ug/mg lysate
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in tris-buffered saline, 0.1% BSA, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to a region between aa125 and 175 of human cell division cycle 23.
SpecificityRecognizes human CDC23/APC8.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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