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You are here:Home » Antibodies » Abs to Cell Division Cycle (CDC) » Anti -CDC7-Related Protein Kinase (Cell Division Cycle 7-related Protein Kinase, CDC7-related Kinase, CDC7, HsCdc7, huCdc7, CDC7L1, Hsk1, MGC117361, MGC126237, MGC126238)

Anti -CDC7-Related Protein Kinase (Cell Division Cycle 7-related Protein Kinase,
CDC7-related Kinase, CDC7, HsCdc7, huCdc7, CDC7L1, Hsk1, MGC117361, MGC126237, MGC126238)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
CDC7L1, CDC7 type protein kinase, regulates firing of the origins of initiation in DNA replication. CDC7L1 forms a complex with a Dbf4-related regulatory subunit to generate an active kinase. Mini-chromosome maintenance protein (MCM) is the major physiological target of Cdc7L1. At least three mRNA variants have been reported. Overexpression of the CDC7L1 protein may be associated with neoplastic transformation for some tumors. CDC7L1 has been documented in a wide range of tissues. One variant is expressed ubiquitously in Human tissues while at least one other has been shown to be testis-specific. ESTs have been isolated from several tissue libraries, including normal embryo, gallbladder, lymph node and thymus and cancerous duodenum and embryo.
Catalog #C2551-01E
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 6.5ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Testis
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.7, 0.01% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the Kinase domain of human CDC7L1.
SpecificityRecognizes human CDC7L1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCell Division Cycle 7 Homolog (S. cerevisiae), EC=2.7.11.1


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