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You are here:Home » Antibodies » Abs to Cancer Markers » Anti -CDCP1 (CUB Domain-containing Protein 1, Membrane Glycoprotein gp140, Subtractive Immunization M Plus HEp3-associated 135kD Protein, SIMA135, Transmembrane and Associated with Src Kinases, CD318, TRASK, UNQ2486/PRO5773) (PE)

Anti -CDCP1 (CUB Domain-containing Protein 1, Membrane Glycoprotein gp140, Subtractive
Immunization M Plus HEp3-associated 135kD Protein, SIMA135, Transmembrane and Associated
with Src Kinases, CD318, TRASK, UNQ2486/PRO5773) (PE)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
CDCP1, also known as SIMA135, is a novel 140kD type I transmembrane glycoprotein with three CUB protein-protein interaction domains in its 635aa extracellular region. The 148aa cytoplasmic region contains canonical phosphorylation sites for Src kinase family members and binding sites for SH3 domains. By alternative splicing, a secreted 310aa residue form of CDCP1 also exists. The amino-terminal region of ~265aa of the type I membrane CDCP1 can also be proteolytically cleaved. CDCP1 is found on the surface of epithelial and bone marrow- derived stem cells. The extracellular region of human CDCP1 shares 84% aa identity with that of the mouse protein.
Catalog #C2566-01K
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Absorption 488nm
Emission 565-605nm
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG1
Clone No12K58
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).
PurityPurified by Protein A/G affinity chromatography.
ImmunogenRecombinant corresponding to aa33-666 from human CDCP1 expressed in NSO cell line.
SpecificityRecognizes an epitope at aa370-666 of human CDCP1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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