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You are here:Home » Antibodies » Abs to Cell Division Cycle (CDC) » Anti -CDK9 (Cyclin-dependent Kinase 9, C-2K, Cell Division Cycle 2-like Protein Kinase 4, Cell Division Protein Kinase 9, Serine/Threonine-protein Kinase PITALRE, CDC2L4)

Anti -CDK9 (Cyclin-dependent Kinase 9, C-2K, Cell Division Cycle 2-like Protein Kinase 4,
Cell Division Protein Kinase 9, Serine/Threonine-protein Kinase PITALRE, CDC2L4)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E B IP IH
IKKalpha, an IkappaB -type protein kinase, is a member of the multimeric IkappaB kinase complex. This complex, often consisting of IKKalpha/IKKbeta heterodimers plus regulatory IKKgamma subunits, phosphorylates IkappaB proteins, marking them for destruction and thereby allowing activation of NFkappaB and downstream nuclear genes. The constitutively expressed IKKalpha protein contains a N-terminal kinase domain, a central leucine zipper motif, and a C-terminal helix-loop-helix motif. In knockout studies, IKKalpha (-/-) mice died perinatally and displayed a range of developmental defects; thus, IKKalpha is believed to function in development, particularly in development of skin keratinocyte, cornea, and conjunctiva.
Catalog #C2579-05C
ApplicationsSuitable for use in Western Blot, ELISA, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:10,000-1:50,000
Western Blot: 1:500-1:3000
Immunohistochemistry (Formalin fixed paraffin embedded): 1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.01% sodium azide.
PuritySerum
ImmunogenSynthetic peptide corresponding to C-terminal and N-terminal domains of human CDK9 (KLH).
SpecificityRecognizes human CDK9.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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