Anti -CDK9 (Cyclin-dependent Kinase 9, C-2K, Cell Division Cycle 2-like Protein Kinase 4,
Cell Division Protein Kinase 9, Serine/Threonine-protein Kinase PITALRE, CDC2L4)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
E B IP IH |
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| IKKalpha, an IkappaB -type protein kinase, is a member of the multimeric IkappaB kinase complex. This complex, often consisting of IKKalpha/IKKbeta heterodimers plus regulatory IKKgamma subunits, phosphorylates IkappaB proteins, marking them for destruction and thereby allowing activation of NFkappaB and downstream nuclear genes. The constitutively expressed IKKalpha protein contains a N-terminal kinase domain, a central leucine zipper motif, and a C-terminal helix-loop-helix motif. In knockout studies, IKKalpha (-/-) mice died perinatally and displayed a range of developmental defects; thus, IKKalpha is believed to function in development, particularly in development of skin keratinocyte, cornea, and conjunctiva. | | | Catalog # | C2579-05C | | Applications | Suitable for use in Western Blot, ELISA, Immunoprecipitation and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:10,000-1:50,000 | | Western Blot: 1:500-1:3000 | | Immunohistochemistry (Formalin fixed paraffin embedded): 1:500 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.01% sodium azide. | | Purity | Serum | | Immunogen | Synthetic peptide corresponding to C-terminal and N-terminal domains of human CDK9 (KLH). | | Specificity | Recognizes human CDK9. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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