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Anti -CDR2 (Yo paraneoplastic antigen, cerebellar degeneration-related protein (62kD), cerebellar degeneration-related antigen-2 (62kD), Cerebellar degeneration-related protein 2, Paraneoplastic cerebellar degeneration-associated antigen, Major Yo paraneoplasti
Anti -CDR2 (Yo paraneoplastic antigen, cerebellar degeneration-related protein (62kD),
cerebellar degeneration-related antigen-2 (62kD), Cerebellar degeneration-related protein
2, Paraneoplastic cerebellar degeneration-associated antigen, Major Yo paraneoplasti
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| Catalog # | C2581-01 | | Recent News | CDR2s Link to PCD (please find the link below). | | www.hhmi.org/news/darnell20071105.html | | Using anti-Yo antibodies, three genes have been cloned (CDR 1-3). CDR2 suppresses the transcriptional activity and DNA binding of nuclear factor-kappa B by an unknown mechanism. The neuron specific expression of CDR2 is regulated by a post-transcriptional mechanism. | | Cellular Localization | Cytoplasmic and Nuclear | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 2ug/ml | | Immunohistochemistry: 5-10ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in Tris-citrate/phosphate, pH 7-8, containing 0.1% sodium azide. | | Purity | Purified by peptide immunoaffinity chromatography. | | Immunogen | Synthetic peptide made to a C-terminal region of the human protein. [Swiss-prot# Q01850]. | | Specificity | Recognizes human CDR2 (Mr 51kd). Species sequence homology | | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Anti-Yo paraneoplastic antigen, cerebellar degeneration-related protein (62kD), cerebellar degeneration-related antigen-2 (62kD), Cerebellar degeneration-related protein 2, Paraneoplastic cerebellar degeneration-associated antigen, Major Yo paraneoplastic |
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