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You are here:Home » Antibodies » Abs to Transcription Factors, Homeobox (HOX) » Anti -CDX2 (Homeobox Protein CDX-2, CDX-3, Caudal-type Homeobox Protein 2, CDX3)

Anti -CDX2 (Homeobox Protein CDX-2, CDX-3, Caudal-type Homeobox Protein 2, CDX3)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
CDX2 is a homeobox protein that binds to the A/T rich sequence in the insulin promoter to stimulate transcription. It is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer. It also plays an important role in maintenance of epithelial lining of the intestines.
Catalog #C2589-57C
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-3ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHCT-116 cells (human colon carcinoma)
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa1-60 of human CDX3/CDX2.
SpecificityRecognizes human CDX2. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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