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You are here:Home » Antibodies » Abs to Cancer Markers » Anti -CEACAM 1,3,4,5,6 (Carcinoembryonic Antigen Related Cell Adhesion Molecule)

Anti -CEACAM 1,3,4,5,6 (Carcinoembryonic Antigen Related Cell Adhesion Molecule)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IP IH FC IF
CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family (13). It consists of seven CEACAM (CEACAM1, CEACAM3-CEACAM8) and 11 pregnancy-specific glyco-protein (PSG1-PSG11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidy inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells.
Catalog #C2589-60
ApplicationsSuitable for use in Immunofluorescence, Flow Cytometry, ELISA, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunofluorescence: 50ug/ml Fixatition: 4% paraformaldehyde, permeabilized with 0.05% saponine. Diluted in PBS with 1% BSA
Immunohistochemistry: Frozen
Optimal dilutions to be determined by the researcher.
Recommended Secondary Antibody IHC/IF
I1904-06F: IgG, H&L (X-Adsorbed) (FITC) Pab Gt xMo
I1904-23: IgG, X-Adsorbed (FITC) Pab Gt xMo
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No5E502
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 40% glycerol.
PurityPurified by Protein G affinity chromatography.
ImmunogenCEA partially purified from a perchloric acid extract from liver metastases of colonic tumors (6).
SpecificityRecognizes human CEACAM1,3,4,5,6.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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