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You are here:Home » Antibodies » Abs to Cancer Markers » Anti -CEACAM 6 (Carcinoembryonic Antigen Related Cell Adhesion Molecule, CEACAM6)

Anti -CEACAM 6 (Carcinoembryonic Antigen Related Cell Adhesion Molecule, CEACAM6)

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Specifications

Clone Host Grade Applications
Polyclonal Mouse Purified B IH
CEA-related cell adhesion molecule 6 (CEACAM6, NCA) belongs to the carcinoembryonic antigen (CEA) gene family. It encodes a glycosyl phosphatidyl inositol GPI)-linked glycoprotein with a Mr of 90kD which is strongly expressed on epithelial cells of the fetal and adult gastrointestinal tract, epithelia of glandular tissues, squamous epithelial cell of the tongue, esophagus and cervix as well as on granulocytes. CEACAM6 expression is upregulated in many adenocarcinomas and leukemias. Like all members of the CEA family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by one immunoglobulin constant-like A and B domain.
Catalog #C2589-79B
ApplicationsSuitable for use in Western Blot and Immunohistochemistry . Other applications not tested.
Recommended DilutionsWestern Blot (Cell lysate):1:500-1:1000 detects a band at ~37.24kD using U-2 OS cells.
Western Blot (Transfected lysate): 1:1000-1:2000 detects a band at ~37.84kD using CEACAM6 transfected 293T lysate
Immunohistochemistry (Paraffin): 3ug/ml using human salivary gland tissue
Optimal dilutions to be determined by the researcher.
Amino Acid SequenceMGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQNRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVPTISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQAHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified
ImmunogenFull length protein corresponding to aa1-344 of human CEACAM6 (AAH05008.1).
SpecificityRecognizes human CEACAM6.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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