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You are here:Home » Antibodies » Abs to Spermatogenesis, Testis Proteins » Anti -CDYL (DKFZP586C1622, chromodomain protein, Y chromosome-like, CDY-like, autosomal, testis-specific chromodomain Y-like protein)

Anti -CDYL (DKFZP586C1622, chromodomain protein, Y chromosome-like, CDY-like, autosomal,
testis-specific chromodomain Y-like protein)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.
Catalog #C2590-10
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:32,000 (detection limit dilution; peptide coated on plate)
Western Blot: 0.1-0.3ug/ml. Approximately 35kDa
band observed in human kidney lysates (calculated MW of 31.1kDa according to
NP_036269.1). The observed molecular weight corresponds to earlier findings in
literature (Pullamsetti et al).
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris-saline, pH 7.3, containing 0.5% BSA and 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide C-SMLKYLQRKIDEF, representing the C-Terminus of the human protein according to NP_004815; NP_736607; NP_736608.
SpecificityRecognizes human CDYL . Species sequence homology: mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDKFZP586C1622, chromodomain protein, Y chromosome-like, CDY-like, autosomal, testis-specific chromodomain Y-like protein


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