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You are here:Home » Antibodies » Abs to Centrosomal Proteins » Anti -CEP170 (CEP170, CEP-170, Centrosomal protein 170kDa, KAB, KARP-1 binding protein, FAM68A)

Anti -CEP170 (CEP170, CEP-170, Centrosomal protein 170kDa, KAB, KARP-1 binding protein,
FAM68A)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined.
Catalog #C2618-01B
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.1% BSA, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenThe epitope recognized by this antibody maps to a region between residue 1534 and the C-teriminus (residue 1584) of human centrosomal protein 170kDa using the numbering given in entry NP_055627.2 (GeneID 9859).
SpecificitySpecies Crossreactivity: Human. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCEP170, CEP-170, Centrosomal protein 170kDa, KAB, KARP-1 binding protein, FAM68A


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