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You are here:Home » Biochemicals » Biochem-Antibiotics » Cercosporamide



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Isolated from Cercosporidium henningsii, cercosporamide was originally identified as a host-selective phytotoxin and broad spectrum antifungal agent. More recently cercosporamide was shown to inhibit a cell wall integrity pathway mediated through a serine/threonine protein kinase, Pkc1, that is central to cell wall biosynthesis. It is both potent (IC50 < 50nM) and selective for Pkc1 kinase inhibition.
Catalog #C2780-40
Molecular Weight~331.3
SolubilitySoluble in ethanol, methanol, DMF or DMSO.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ethanol, methanol, DMF or DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number131436-22-1
Molecular FormulaC16H13NO7
Molecular Weight331.3
SourceCercosporidium sp. MST-FP1899
Purity95% by HPLC
FormSupplied as a dark tan lyophilisate.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.

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