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You are here:Home » Antibodies » Abs to Neuroscience » Anti -Cerebellin-1, CT (Cerebellin 1, CBLN1, Cerebellin 1 Precursor, Precerebellin)

Anti -Cerebellin-1, CT (Cerebellin 1, CBLN1, Cerebellin 1 Precursor, Precerebellin)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Precerebellin is required for synapse integrity and synaptic plasticity and for the ER export and secretion of CBLN3. Precerebellin exerts neuromodulatory functions including directly stimulating norepinephrine release via the adenylate cyclase/PKA-dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release. Research indicates that Precerebellin may also be involved in a wider range of functions than have been so far demonstrated.
Catalog #C2790-55
ApplicationsSuitable for use in Immunohistochemistry (frozen) and Western Blot. Other applications not tested.
Recommended Dilutionimmunohistochemistry (frozen): 10ug/ml
Western Blot: 2-4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenA peptide corresponding to an 16aa sequence from near the carboxy terminus of human Precerebellin.
SpecificityRecognizes human CBLN1. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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