CERT, aa347-598, Recombinant, Human (Ceramide transfer protein, CERTL, Collagen type IV alpha-3-binding protein, FLJ20597, Goodpasture antigen-binding protein, GPBP, hCERT, StARD11, STARD11, StAR-related lipid transfer protein 11, START domain-containing
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| CERT is a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. | | | Catalog # | C2899-02 | | Source | Recombinant corresponding to aa347-598 of human CERT 6x his tagged expressed in E.coli. | | AA Sequences | MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWAGSMLH WPTSLPSGDA FSSVGTHRFV QKVEEMVQNH MTYSLQDVGG DANWQLVVEE GEMKVYRREV EENGIVLDPL KATHAVKGVT GHEVCNYFWN VDVRNDWETT IENFHVVETL ADNAIIIYQT HKRVWPASQR DVLYLSVIRK IPALTENDPE TWIVCNFSVD HDSAPLNNRC VRAKINVAMI CQTLVSPPEG NQEISRDNIL CKITYVANVN PGGWAPASVL RAVAKREYPK FLKRFTSYVQ EKTAGKPILF | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 33.1kD | | Source | E.coli | | Purity | ~95% (SDS-PAGE) | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol, 0.1M sodium chloride. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for CERT, aa347-598, Recombinant, Human (Ceramide transfer protein, CERTL, Collagen type IV alpha-3-binding protein, FLJ20597, Goodpasture antigen-binding protein, GPBP, hCERT, StARD11, STARD11, StAR-related lipid transfer protein 11, START domain-containing |
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