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Cerulenin (2,3-Epoxy-4-oxo-7,10-dodecadienamide)
Cerulenin (2,3-Epoxy-4-oxo-7,10-dodecadienamide)
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| Antibiotic. Fatty acid synthase (FAS) inhibitor, reported to bind in equimolar ratio to B-keto-acyl- ACP synthase, thus inhibiting protein acylation. Produces metabolic effects similar to effects of leptin, but through mechanisms that are independent of, or down-stream from, both leptin and melanocortin receptors. Apoptosis inducer. Inhibitor of bacterial fatty acid synthesis (inhibits FabH, FabB and FabF condensation enzymes). | | | Catalog # | C2900-16 | | MOLECULAR FORMULA | C12H17NO3 | | MOLECULAR WEIGHT: 223.3 | | PURITY: 98% | | APPEARANCE: White to off-white powder | | SOLUBILITY: Soluble in DMSO (20mg/ml), dimethyl formamide (20mg/ml), dichloromethane (5mg/ml), methanol, 100% ethanol (20mg/ml) or acetone; slighly soluble in water. | | Storage and Stability | May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. | | CAS Number | 17397-89-6 | | Molecular Formula | C12H17NO3 | | Molecular Weight | 223.3 | | Purity | 98%. Purified | | Form | Supplied as a white to off-white powder. Soluble in 20mg/ml DMSO, 20mg/ml dimethyl formamide, 5mg/ml dichloromethane, 20mg/ml methanol, 100% ethanol or acetone; slighly soluble in water. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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