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You are here:Home » Biochemicals » Biochem-Antibiotics » Cerulenin (2,3-Epoxy-4-oxo-7,10-dodecadienamide)

Cerulenin (2,3-Epoxy-4-oxo-7,10-dodecadienamide)

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Specifications

Antibiotic. Fatty acid synthase (FAS) inhibitor, reported to bind in equimolar ratio to B-keto-acyl- ACP synthase, thus inhibiting protein acylation. Produces metabolic effects similar to effects of leptin, but through mechanisms that are independent of, or down-stream from, both leptin and melanocortin receptors. Apoptosis inducer. Inhibitor of bacterial fatty acid synthesis (inhibits FabH, FabB and FabF condensation enzymes).
Catalog #C2900-16
MOLECULAR FORMULA C12H17NO3
MOLECULAR WEIGHT: 223.3
PURITY: 98%
APPEARANCE: White to off-white powder
SOLUBILITY: Soluble in DMSO (20mg/ml), dimethyl formamide (20mg/ml), dichloromethane (5mg/ml), methanol, 100% ethanol (20mg/ml) or acetone; slighly soluble in water.
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze.
CAS Number17397-89-6
Molecular FormulaC12H17NO3
Molecular Weight223.3
Purity98%. Purified
FormSupplied as a white to off-white powder. Soluble in 20mg/ml DMSO, 20mg/ml dimethyl formamide, 5mg/ml dichloromethane, 20mg/ml methanol, 100% ethanol or acetone; slighly soluble in water.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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