Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Serum Proteins » Anti -CETP (Cholesteryl Ester Transfer Protein)

Anti -CETP (Cholesteryl Ester Transfer Protein)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IP
It has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to specifically accelerate the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general, elevated levels of CETP have been associated with increased risk of coronary heart disease.
Catalog #C3050-01
ApplicationsSuitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionsWestern Blot: 1:400. Detects a doublet at ~70kD from human serum representing CETP.
Immunoprecipitation: Immunoprecipitates CETP activity from serum samples using Protein G.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypeMonoclonal
IsotypeIgG1
Clone No5D2
HostMouse
SourceHuman
Concentration~2mg/ml
FormSupplied as a liquid in PBS, 0.05% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa131-142, CDSGRVRTDAPD from the C-terminal of human CETP protein.
Cellular LocalizationSecreted
SpecificityRecognizes human cholesteryl ester transfer protein (CETP). Species Crossreactivity: rabbit
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links