Anti -cGMP Binding cGMP-Specific Phosphodiesterase V (PDE5, PDE5A, CN5A, PDE5,CGB-PDE,
phosphodiesterase 5A, cGMP-specific, cGMP-binding cGMP-specific 3', 5'-cyclic nucleotide
phosphodiesterase)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. | | | Catalog # | C3400-01A | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris-saline, pH 7.2. 0.5% BSA, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide C-LINGESGQAKRN, representing the C-Terminus of the human protein sequence according to NP_001074; NP_237223; NP_246273; (NP_236914). | | Specificity | Nizes human PDE5A. Species Crossreactivity: rat and canine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | PDE5, PDE5A, CN5A, PDE5,CGB-PDE, phosphodiesterase 5A, cGMP-specific, cGMP-binding cGMP-specific 3', 5'-cyclic nucleotide phosphodiesterase |
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