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Specifications

Chaetocin is an epithiodioxopiperazine antibiotic that has recently shown promise as a selective antitumor agent. Chaetocin is a specific inhibitor for the lysine-specific methyltransferase SU(VAR)3-9 both in vitro and in vivo. Chaetocin is dramatically accumulated in cancer cells via a process inhibited by glutathione. Inside the cell, its activity is mediated by the imposition of oxidative stress.
Catalog #	C3430-45
	DMSO, DMF, methanol and ethanol. Poorly soluble in water
CAS Number	28097-03-2
Molecular Formula	C30H28N6O6S4
Molecular Weight	696.85
Source	Chaetomium sp.
Purity	> 99% by HPLC
Form	White solid
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	Chetocin